Plant sterols in atherosclerosis prevention

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No association between plasma levels of plant sterols and atherosclerosis in mice and men.

OBJECTIVE Sitosterolemia is characterized by elevated plasma levels of plant sterols, hypercholesterolemia and premature coronary heart disease (CHD). CHD develops in some subjects with sitosterolemia, despite having normal plasma cholesterol levels, suggesting that high circulating levels of plant sterols may be atherogenic. We tested whether elevated plasma levels of plant sterols (sitosterol...

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Plant Sterols and Sterolins Monograph

Alternative Medicine Review ◆ Volume 6, Number 2 ◆ 2001 Page 203 Plant Sterols and Sterolins Introduction Sterols and sterolins, also known as phytosterols, are fats present in all plants, including fruits and vegetables. Although they are chemically similar to the animal fat, cholesterol, they have been shown to exert significant unique biochemical effects in both animals and humans. Because t...

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Serum plant sterols and atherosclerosis: is there a place for statin-ezetimibe combination?

We read with interest the paper by Miettinen et al. (1) demonstrating that the higher the absorption of cholesterol, the higher the plant sterol contents are in serum resulting in their higher contents in atherosclerotic plaque. The prospective Cardiovascular Munster (PROCAM) study found that people in the upper quartile of sitosterol levels had a 1.8-fold increased risk of major coronary event...

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Increased plasma levels of plant sterols and atherosclerosis: a controversial issue.

A number of studies have raised the possibility of circulating plant sterols being a risk factor in the pathogenesis of atherosclerosis. Evidence in support of this hypothesis comes mainly from observations in sitosterolemic patients, who hyperabsorb plant sterols and suffer premature atherosclerosis. Accordingly, the atherogenicity of plant sterols of dietary origin is currently under debate, ...

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ژورنال

عنوان ژورنال: The American Journal of Clinical Nutrition

سال: 2010

ISSN: 0002-9165,1938-3207

DOI: 10.3945/ajcn.2010.29828